DHLA Nano-Plex (with Resveratrol) - 8oz
For the first time in history, Premier Research Labs have developed a
stable, fully reduced form of lipoic acid (DHLA) derived from
"once-living" sources and the not typical synthetic sources. Now you
can obtain the tremendous amounts of exquisitely bio-available DHLA,
fully active and intracellularly potent. DHLA Nano-Plex is vastly superior to alpha-lipoic acid (ALA) or R-lipoic acid in free radical
reducing capacity. Thus DHLA Nano-Plex can deliver more comprehensive reduction of oxidative stress for literally
every organ and gland, especially the brain and the nervous system. For example, DHLA can
reduce the superoxide anion free radical and the peroxyl radical whereas ALA and R-lipoic acid cannot. In Premier Research Lab's patent-pending process, DHLA Nano-Plex is produced by 12 strains of beneficial probiotic
organisms that are micro-digested into particle sizes so tiny they become exceptionally bio-available. Just
¼ teaspoon provides 50 mg of DHLA, 36 mg of R-lipoic and 5 mg of Resveratrol.
There is no
other direct DHLA supplement available in the world! The closest you
might come is a product with 50 mg of alpha-lipoic or R-lipoic acid
which usually derived from synthetic sources.*
Also available in 2oz size
DHLA Nano-PlexRecommended Use: ¼ teaspoon in water/juice 1-2 times/day. Shake gently before use.
Container
Size: 2 or 8 ounces
Ingredients: Proprietary
blend 1.25ml - Stabilized DHLA (80mg), S-Lipoic Acid, Tumeric (rhizome), Bifidobbacterium Species, Enterococcus Species,
Lactobacillus Species, Streptcoccus therm.
Other Ingredients: Purified
water, certified organic alcohol
* These statements have not been evaluated by the Food and Drug
Administration. This health product is not intended to diagnose, treat, cure or
prevent disease.
DHLA: The Spectacular Antioxidant
DHLA (dihydrolipoic acid) is unique as an antioxidant due to its
spectacular effectiveness in quenching every known free radical that
occurs in living tissue, including both fat and water soluble tissues.
No other antioxidant has this incredible capability. DHLA is readily
absorbed orally and has very low toxicity. It has unequalled potential
as a highly effective therapeutic agent in clinical conditions
associated with free radical damage such as Parkinson's disease,
Alzheimer's disease and other neurodegenerative illnesses. (1)
Until 2003, DHLA in a stabilized form was not
available. DHLA could only be obtained indirectly through consuming
ALA (alpha lipoic acid) which in turn, was converted by the body into
small amounts of DHLA. However, this process did not deliver a
significant or reliable supply of DHLA. Research studies have
attempted to measure the effect of DHLA on cellular tissue using
indirect methods based on ALA consumption. As a result, DHLA is known
to be a powerful electron donor to other compounds. Ascorbic acid and
indirectly vitamin E are regenerated by DHLA. (2) Busse et. al. found
that the oxidized form of DHLA, ALA, increased intracellular
glutathione. (3) DHLA was shown to regenerate coenzyme QIO,
glutathione and NADPH or NADH and by this mechanism, increase cellular
ATP production.(4) The oxidized form of DHLA, ALA, also assists in the
conversion of pyruvate to acetyl-coenzyme A, the beginning point of the
Krebs cycle which produces the high energy molecule ATP.
Radical Synthetic vs. "Once Living" Sources
ALA, R-lipoic acid or DHLA that are derived from synthetic sources can
never match natural source counterparts in the ability to sustain and
repair the DNA of the cell. A natural ("once living") source is
comprised of dynamic, complex processes where each molecule contains
atoms that generate photons, or in other words, pure light. The
photonic field around each molecule creates a "body of light" which
surrounds all living substances. Only nutrients derived from a "once
living" source are capable of upgrading cellular DNA, according to
quantum physics researcher and expert, Dr. Fritz-Albert Popp. (33)
On the other hand, synthetic source nutrients may provide
initial cellular benefits, but over time, they act to accelerate the
degeneration of DNA, ending in earlier cell death. Synthetic nutrients
initially stimulate the cell to accomplish work which may appear to be
beneficial, but long-term, the DNA and cellular degradation cannot
justify the initial benefits. Consequently, using ALA derived from a
synthetic source can defeat the purpose of using an ALA supplement to
live longer more healthfully. Not only has a stable form of DHLA been
badly needed, but also a DHLA source that has been derived from a "once
living" source so it is capable of imparting significant, long-term DNA
protection and cellular benefits.
Benefits of Alpha Lipoic Acid
Many research studies show the spectacular benefits from the use of
ALA, even ALA derived from synthetic sources. Although these studies
demonstrate many, short-term benefits of synthetic ALA, they do
not test for or warn against the long-term problems encountered in
consuming synthetically derived agents.
Unfortunately, most research studies using ALA have used the
synthetic form which contains equal amounts of the R and the S racemic
forms. The S form occurs only in synthetic source ALA, never in
naturally-derived ALA, and has negative, pro-inflammatory effects. In
an attempt to enhance the effectiveness of synthetic ALA, some
manufacturers have chemically removed the S-form, thus producing a new
form, stand alone R-lipoic acid. Because synthetically derived ALA
contains both R and S forms, studies show that synthetic R-lipoic acid
alone is superior to ALA (which contains both R and S forms). However, new research since the year 2000
has shown the S-form of lipoic acid (which has pro-inflammatory
effects) may well be the cause of this pro-oxidant study finding
(rather than as an effect of DHLA).
Benefits of Stabilized DHLA
The above clinical research studies using synthetically-derived ALA had
obviously spectacular physiological benefits. However, as has been
emphasized earlier, these benefits are not without a price to pay,
namely, the eventual degradation of the cellular DNA which occurs
during long-term use of synthetic compounds.
Advantages of Natural-Source DHLA
Stabilized DHLA (natural-source) may prove to be one of the most
significant antioxidant compounds ever created, since it can accomplish
all the feats attributed to ALA and more, but without ALA's negative
effects. In fact, some authors believe that the benefits ascribed to
ALA are in fact, actually due to the internal generation of DHLA (after
ALA consumption). For the very first time, stabilized DHLA is now
available that can offer significant and reliable amounts of DHLA,
without the need to consume synthetic precursors.
DNA and Nerve Protection
Stabilized DHLA can provide exquisite neuroprotection as well as
superior DNA protection and repair, unmatchable by any other
antioxidant. Studies show that DHLA increases cellular energy and
efficiency by increasing ATP. At the same time, DHLA helps regenerate
the production of vitamin E, CoQIO, glutathione, NADH and NADPH to
provide unparalleled DNA protection. In addition, DHLA has the capacity
to induce repair of DNA strand breaks.7 For long-term benefits of DHLA,
only natural-source DHLA is recommended to avoid the long-term
degradation of DNA from synthetically-derived sources.
Arterial and Heart Protection
Research has shown that DHLA can accelerate recovery of the aortic
blood flow during reperfusion (resumption of blood flow) and increase
ATP synthesis in the rat heart.27 ALA forms were not helpful only
internally generated DHLA was able to reduce the infarct or necrotic
tissue size in middle cerebral artery occlusion in mice.28 Wolz et. al.
believe ALA must be reduced to the DHLA form in order to provide
neuroprotection.29 Natural-source, stabilized DHLA (now available) can
provide exquisite neuroprotection as well as superior DNA repair and
protection without compromise.
DHLA: Safety and Effectiveness
Clinical
research by Dr. Robert J. Marshall has shown that the newly available
natural-source, stabilized DHLA is both safe and effective for general
use, including
those with chronic illness and neurodegenerative disease. If high
dosages (over 300 mg/day) of stabilized DHLA are used, to get maximum
benefits the concurrent use of additional nutrients such as nutritional
yeast which contains natural-source B vitamins, sulphur-based amino
acids and reduced glutathione, is an excellent adjunct.
Brief Clinical Observations
The discoverer and inventor of stabilized DHLA, Dr. Marshall, has
observed various immediate, spectacular effects of oral administration
of stabilized DHLA in his office.
One 44-year woman presented with a history of bilateral,
maxillary sinus infection with extreme pain even to the touch. She had
used oral antiobiotics for more than a year with no relief and was
unable to breathe through her sinuses for at least 10 months. Further,
she had begun to experience pain at her liver, chronic fatigue, loose
stool and severe brain fog. After only one dose (30 drops) of
natural-source, stabilized DHLA, within less than one minute, she
remarked, "I can breathe through my nose! My head feels clear for the
first time in 10 months."
A 60 year-old male complaining of brain fog, diminished
short-term memory and a general sense of malaise remarked that within
one day of taking natural-source, stablilized DHLA, literally all his
symptoms were gone. He had a renewed sense of mental acuity and a
significant improvement in short-term memory.
A medical doctor has remarked that in many clinical cases,
natural-source, stabilized DHLA reduced the amount of time and number
of nutritional supplements needed to restore healthy nerve function in
his patients. It has become one of his most used supplement "aces",
especially in neurodegenerative cases.
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